Dragon Tribe
When compared, the power of Dragon Tribe in Teamfight Tactics resembles a sine wave graph. This trait is extremely weak when first activated and only becomes strong at the moment the eggs hatch. As the game progresses towards the late stage, Dragon Tribe shows its vulnerabilities as it no longer provides stats or damage amplification effects, nor defensive capabilities for champions. If you aren’t lucky enough to upgrade many Dragon Tribe champions to 3 stars, you risk being easily eliminated early.
Therefore, the best way to utilize the Dragon Tribe effect is to activate it early and then focus on upgrading a carry to 3 stars (usually Ashe or Zyra). Once you achieve that goal, you should sell unnecessary Dragon Tribe units like Udyr or Sett to make room for more useful pieces. If you aim for a Marksman team, Kindred and Aphelios are stronger options late game. Additionally, you can use Brand, Viktor… to activate the Sorcerer effect with Zyra.
Bruiser
Despite having a powerful 5-cost unit in Volibear, the Bruiser system is still primarily a good defensive option early game. Before reaching level 6, most players do not have a strong enough carry with superior damage. At that time, the large health pool of the Bruiser system proves to be an extremely effective defensive strategy. Moreover, with 2 one-cost units like Gragas and Warwick, players can easily upgrade their Bruiser lineup early.
However, as the match progresses into the late game, the large health pool of Bruisers loses its significance. Units like Karma, Draven, Vel’Koz… will have enough damage to easily wipe out Bruiser pieces. Therefore, you should only use the Bruiser system as your primary frontline in the early and mid-game. By the late game, options like the Armor trait, Knight system, or Cavalry… are far more effective defensive choices.
Regen
As mentioned above, the lack of high-damage champions for players before level 6 significantly lowers the chances of quickly eliminating opponents. Therefore, the natural healing effect of the Regen system proves to be extremely powerful and can frustrate opponents considerably. If you have a 3-star Vladimir, opponents will have almost no way to eliminate a unit that is both “tanky” and has strong healing.
Despite being strong, the Regen system is extremely weak late game when opponents have a full roster of damage and control effects in their team. Indeed, Vladimir is very strong and resilient, but this unit cannot do much if controlled, aside from armor/magic resistance and taking continuous damage. Thus, a 4 Regen lineup is only strong if you upgrade Vladimir to 3 stars early and snowball the match. Clearly, employing a hyper-roll strategy in the current meta is a very poor idea.